Insecticidal agent 21

CAT: 0804-HY-173413Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-173413Size:1 Each
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Description
Insecticidal agent 21 (Compound 6) is an insecticide that is effective against Culex pipiens larvae (LC50: 0.4 μg/mL) . Insecticidal agent 21 achieves multi-target neurotoxicity by inhibiting acetylcholinesterase (AChE) and simultaneously targeting other neural receptors (nicotinic acetylcholine receptors (nAChR), voltage-gated sodium channels (VGSC), and γ-aminobutyric acid receptors (GABAAR) ) . Insecticidal agent 21 has a strong insecticidal effect and can be used in the development of new insecticides to address the problem of mosquito resistance to traditional insecticides[1].
CAS Number
[3082443-45-3]
UNSPSC
12352005
Target
Cholinesterase (ChE) ; GABA Receptor; Insecticide; nAChR; Sodium Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Smiles
CCCCCCCCCCCC(NN1C(/C(C=C1C2=CC=C(C)C=C2)=C/C3=CC4=CC=C5C(C=CC=C5)=C4N=C3Cl)=O)=O
Molecular Formula
C37H40ClN3O2
Molecular Weight
594.19
References & Citations
[1]El-Helw EAE, et al. Synthesis of Benzo[h]quinoline derivatives and evaluation of their insecticidal activity against Culex pipiens L. larvae. Eur J Med Chem. 2025 Jun 5;290:117565.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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