Products for Research Use Only
RegisterLogin

FDU73

CAT: 0804-HY-173125Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-173125Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
FDU73 is a highly effective and selective BTK PROTAC degrader with a DC50 of 2.9 nM (in JeKo-1 cells). FDU73 can inhibit the proliferation of tumor cells and exhibits anti-tumor activity[1]. (Pink: BTK ligand-14 ; Black: Linker (HY-168297) ; Blue: E3 ligase ligand 59 (HY-173378) ; E3 ligase ligand+Linker (HY-173127) )
UNSPSC
12352005
Target
Btk; PROTACs
Related Pathways
PROTAC; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(N[C@@H]1C[C@@H](NC2=C3C(NC=C3C(C4=CC=C(OC5=CC=CC=C5)C=C4)=O)=NC=N2)CC1)CC6CCN(CCC7CCN(C8=NC=C(C(CC9)C(NC9=O)=O)C=C8)CC7)CC6
Molecular Formula
C48H55N9O5
Molecular Weight
838.01
References & Citations
[1]Lin Y, et al. Design, synthesis, and biological evaluation of novel BTK-targeting proteolysis targeting chimeras (PROTACs) with enhanced pharmacokinetic properties. Eur J Med Chem. 2025 Feb 22;289:117420.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
T206226-01FDU73

Popular Products