Products for Research Use Only
RegisterLogin

FtsZ-IN-12

CAT: 0804-HY-173054Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-173054Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
FtsZ-IN-12 (Compound 16e) is the inhibitor for filamentous temperature-sensitive mutant Z (FtsZ) that promotes the polymerization of FtsZ protein, inhibits its GTPase activity, thereby interfering with bacterial cell division process. FtsZ-IN-12 exhibits boardspectrum antibacterial activity that inhibits B. subtilis ATCC9372, B. pumilus CMCC63202, S. aureus ATCC25923, E. coli BW25113 and A. baumannii ATCC19606 with MIC of 0.062-1 μg/mL. FtsZ-IN-12 inhibits the formation of bacterial biofilms and exhibits a clearing effect on mature biofilms. FtsZ-IN-12 exhibits bactericidal activity without hemolytic toxicity to mammalian red blood cells (15 mg/kg) [1].
CAS Number
3099249-36-9
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
C[N+]1=CC=C(NC2=CC3=C(N(CCC4CCCCC4)C=C3)C=C2)C=C1C5=CC=CC=C5.[I-]
Molecular Formula
C28H32IN3
Molecular Weight
537.48
References & Citations
[1]Ma Y, et al., Design, Synthesis, and Bioactivity Evaluation of Novel 1-Methyl-2-phenylpyridin-1-ium Derivatives as Broad-Spectrum FtsZ Inhibitors. J Agric Food Chem. 2025 Feb 26;73 (8) :4958-4975.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-168630FtsZ-IN-11
HY-149223FtsZ-IN-5
HY-150754FtsZ-IN-4
HY-149226FtsZ-IN-8
HY-146595FtsZ-IN-1
HY-161148FtsZ-IN-9
HY-W773487FtsZ-IN-10
HY-149224FtsZ-IN-6
HY-146330FtsZ-IN-2
HY-149225FtsZ-IN-7

Alternative Products

CatalogName
GTR19249935-01FtsZ-IN-12
563065-01FtsZ
abx319936-01Cell Division Protein FtsZ (ftsZ) Antibody
GTR17882516-01FtsZ Antibody
T206344-01FtsZ-IN-13
T61737-01FtsZ-IN-4
MBS543704-01FtsZ Peptide
MBS5806220FtsZ-IN-1
MBS5806040FtsZ-IN-2
MBS5816727FtsZ-IN-6

Popular Products