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YL-1-9YL-1-9 - High-quality laboratory reagent available from Gentaur. Catalog: 804-HY-172597.804-HY-172597804-HY-172597Business & Industrial > Science & LaboratoryYL-1-9
Gentaur
EUR12027-02-23

YL-1-9

CAT:
804-HY-172597
Size:
1 Each
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
YL-1-9 - image 1

YL-1-9

  • Description:

    YL-1-9 is an inhibitor of the degradation of p53 by MDM2 through strong binding to the key hydrophobic pockets of MDM2. YL-1-9 induces cell cycle arrest and apoptosis in breast cancer cells[1].

  • UNSPSC:

    12352005

  • Target:

    Apoptosis; CDK; MDM-2/p53

  • Related Pathways:

    Apoptosis; Cell Cycle/DNA Damage

  • Applications:

    Cancer-Kinase/protease

  • Field of Research:

    Cancer

  • Smiles:

    O=C(NC1=CC(C(F)(F)F)=C(CN2CCC(C)CC2)C=C1)C3=CC(OCO4)=C4C=C3

  • Molecular Formula:

    C22H23F3N2O3

  • Molecular Weight:

    420.42

  • References & Citations:

    [1]Chongyun Zhou, et al. The novel Piperine derivative YL-1-9 exhibits anti-breast Cancer effects by inducing apoptosis via the p53/p21 pathway. Bioorg Med Chem Lett. 2025 Aug 1:123:130231.

  • Shipping Conditions:

    Room temperature

  • Scientific Category:

    Reference compound1

  • Clinical Information:

    No Development Reported

  • CAS Number:

    [3064304-12-4]

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