DSPE-PEG5000-K237

• Description:

  DSPE-PEG5000-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237) . K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG5000-K237 can be used for drug delivery[1].

• UNSPSC:

  12352200

• Target:

  Liposome

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  [Mal-Cys-HTMYYHHYQHHL]C(CCOCCOC(NCCOP(OC[C@](COC(CCCCCCCCCCCCCCCCC)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O.[n]

• Molecular Weight:

  5000 (Average)

• References & Citations:

  [1]Hetian L, et al. A novel peptide isolated from a phage display library inhibits tumor growth and metastasis by blocking the binding of vascular endothelial growth factor to its kinase domain receptor. J Biol Chem. 2002 Nov 8;277 (45) :43137-42.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Biochemical Assay Reagents

• Clinical Information:

  No Development Reported