DSPE-PEG5000-cRGD

• Description:

  DSPE-PEG5000-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD) . cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG5000-cRGD can be used for drug delivery[1].

• UNSPSC:

  12352200

• Target:

  Integrin; Liposome

• Related Pathways:

  Cytoskeleton; Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  [Cyclo (RGD-{d-Phe}-K) ]C (CCOCCOC (NCCOP (OC[C@] (COC (CCCCCCCCCCCCCCCCC) =O) ([H]) OC (CCCCCCCCCCCCCCCCC) =O) (O) =O) =O) =O.[n]

• Molecular Weight:

  5000 (Average)

• References & Citations:

  [1]Gajbhiye KR, et al. cRGD functionalised nanocarriers for targeted delivery of bioactives. J Drug Target. 2019 Feb;27 (2) :111-124.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Biochemical Assay Reagents

• Clinical Information:

  No Development Reported