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XT17

CAT: 0804-HY-172264Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-172264Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
XT17 is an anthrone compound with broad-spectrum antibacterial activity. It exerts its antibacterial effect by disrupting the cell wall and inhibiting DNA synthesis. XT17 exhibits weak hemolytic activity, low cytotoxicity against mammalian cell lines, and a low frequency of drug resistance. Meanwhile, XT17 shows in vivo efficacy in a mouse corneal infection model induced by Staphylococcus aureus or Pseudomonas aeruginosa. Further docking studies have confirmed that XT17 can form a stable complex with bacterial gyrase. XT17 can be used in the research of the anti - infection field[1].
UNSPSC
12352211
Target
Antibiotic; Bacterial; DNA/RNA Synthesis
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Infection
Smiles
O=C1C2=CC=C(OCCCNC(N)=N)C=C2OC3=C1C(OC/C=C(C)\C)=CC(OCCCNC(N)=N)=C3
Molecular Formula
C26H34N6O5
Molecular Weight
510.59
References & Citations
[1]Li H, et al. Development of xanthone derivatives as effective broad-spectrum antimicrobials: Disrupting cell wall and inhibiting DNA synthesis. Sci Adv. 2025 Mar 7;11 (10) :eadt4723.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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