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ER ligand-9

CAT: 0804-HY-172067Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-172067Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ER ligand-9 is a conjugate of an estrogen receptor (Estrogen Receptor/ERR) and a linker, which can be used to synthesize PROTAC ERD-1233.
CAS Number
3026011-20-8
UNSPSC
12352005
Target
Estrogen Receptor/ERR; Target Protein Ligand-Linker Conjugates
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
OC1=CC=C([C@@H](C2=CC=C(N3CCC4(CC(CO4)C=O)CC3)C=C2)[C@@H](C5=CC=CC=C5)CC6)C6=C1
Molecular Formula
C31H33NO3
Molecular Weight
467.60
References & Citations
[1]Ranjan Kumar Acharyya, et al. Discovery of ERD-1233 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader for the Treatment of ER+ Human Breast Cancer. J Med Chem. 2024 Nov 14;67 (21) :19010-19037.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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