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Erufosine

CAT: 0804-HY-171777Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-171777Size:1 Each
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Description
Erufosine is an inhibitor of PI3K/Akt and Ras/Raf/MAPK signaling pathways. Erufosine inhibits the activity of breast cancer cell lines MCF-7 and MDA-MB 231 (IC50: 40.95/40.8 μM) . Erufosine reduces the phosphorylation of PI3K (p85), Akt (PKB), and cRaf. Erufosine can be used in the study of breast cancer and myeloid leukemia[1].
CAS Number
202867-33-2
Product Name Alternative
ErPC3; Erucylphosphohomocholine
UNSPSC
12352128
Target
Akt; p38 MAPK; PI3K; Raf; Ras
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
CCCCCCCC/C=C\CCCCCCCCCCCCOP(OCCC[N+](C)(C)C)([O-])=O
Molecular Formula
C28H58NO4P
Molecular Weight
503.74
References & Citations
[1]Dineva IK, et al. Erufosine suppresses breast cancer in vitro and in vivo for its activity on PI3K, c-Raf and Akt proteins. J Cancer Res Clin Oncol. 2012 Nov;138 (11) :1909-17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
T211021-01Erufosine

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