Antimicrobial agent-39

CAT: 0804-HY-170993Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-170993Size:1 Each
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Description
Antimicrobial agent-39 (Compound 8i) is an antibiotic that targets 50S ribosomal subunit and inhibits bacterial protein synthesis. Antimicrobial agent-39 disrupts bacterial cell membranes, leads to leakage of cell contents, thereby exhibiting board-spectrum actibacterial activity. Antimicrobial agent-39 targets organic cation transporters (OCTs), accumulates in infected kidneys, thereby ameliorating pyelonephritis in mouse models[1].
UNSPSC
12352005
Target
Antibiotic; Bacterial
Related Pathways
Anti-infection
Field of Research
Infection; Inflammation/Immunology
Smiles
O=C1[C@]2([H])[C@@]([C@@H](C)[C@H](O)[C@@](C=C)(C)C[C@@H](OC(CSC3=NC(C=C[N+](CC4=CC=C(C)C=C4)=C5)=C5N3)=O)[C@@]26C)(CC[C@H]6C)CC1.[Br-]
Molecular Formula
C36H46BrN3O4S
Molecular Weight
696.74
References & Citations
[1]Tian L, et al., Kidney Targeting Smart Antibiotic Discovery: Multimechanism Pleuromutilins for Pyelonephritis Therapy. J Med Chem. 2025 Feb 13;68 (3) :3335-3355.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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