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PIKfyve-IN-4

CAT: 0804-HY-170909-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-170909-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PIKfyve-IN-4 (Compound 40) is an orally active and selective inhibitor of phosphatidylinositol-3-phosphate 5-kinase (PIKfyve), with an IC50 of 0.60 nM. PIKfyve-IN-4 exhibits good systemic tolerance[1].
UNSPSC
12352005
Target
PIKfyve
Related Pathways
PI3K/Akt/mTOR
Field of Research
Others
Purity
99.53
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC1=NC=CC(C2=CNC3=C2C=C(C#CCSC)C=C3)=N1
Molecular Formula
C16H14N4S
Molecular Weight
294.37
References & Citations
[1]Min SM, et al. Development of a Second-Generation, In Vivo Chemical Probe for PIKfyve. J Med Chem. 2025 Feb 13;68 (3) :3282-3308.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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