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TZEP7

CAT: 0804-HY-170787Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-170787Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TZEP7 is an EGFR kinase inhibitior in cancer cells. TZEP7 exhibits cytotoxic effects against cancer cell lines and induces apoptosis. TZEP7 demonstrates downregulation of antiapoptotic Bcl-2, upregulation of pro-apoptotic Bax, and increases caspase levels. TZEP7 is promising for research of anticancer agent[1].
CAS Number
2566714-41-6
UNSPSC
12352005
Target
Apoptosis; Bcl-2 Family; Caspase; EGFR
Related Pathways
Apoptosis; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
ClC1=CC=C(C2=CC(C3=CC(C)=C(F)C=C3)=NC/C(S2)=C/C#CC4=CC=CC=C4)C=C1
Molecular Formula
C27H19ClFNS
Molecular Weight
443.96
References & Citations
[1]Atmaca H, et al. Novel Enyne-Modified 1,4-Thiazepines as Epidermal Growth Factor Receptor Inhibitors: Anticancer and Computational Studies. ACS Omega. 2024 Dec 26;10 (1) :821-832.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19249425-01TZEP7

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