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GB2095

CAT: 0804-HY-170510-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-170510-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GB2095 is an orally active and selective galectin-3 inhibitor. GB2095 shows superior selectivity for both human (KD = 0.036 μM) and mouse galectin-3 (KD = 0.35 μM) over other galectins (such as h-Gal-1/4N/4C/8N/8C/9N/9C and m-galectin-1) . GB2095 inhibits tumor growth in syngeneic mouse models of breast and melanoma cancers. GB2095 can be used for breast and melanoma cancer research[1].
CAS Number
2574415-75-9
UNSPSC
12352005
Target
Galectin
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.92
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@@H](N2C=C(C3=CC(F)=C(C(F)=C3)Cl)C=N2)[C@H]([C@H](O[C@@H]1SC4=CN=CC(Br)=C4)CO)O
Molecular Formula
C20H17BrClF2N3O4S
Molecular Weight
548.79
References & Citations
[1]Peterson K, et al., Development and Characterization of a High-Affinity Selective Galectin-3 Mouse Tool Compound in Mouse Models of Cancer. J Med Chem. 2024 Dec 26;67 (24) :21905-21915.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
GTR19250506-01GB2095

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