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LZ9

CAT: 0804-HY-170306Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-170306Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LZ9 is a ATP-competitive CDK1 and CDK2 inhibitor. LZ9 has the potential for the research of colorectal cancer (CRC) [1][2].
CAS Number
844441-29-8
UNSPSC
12352005
Target
CDK
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C(C1=NNC=C1NC(C2=C(F)C=CC=C2F)=O)NC3=CC=C(C=C3)F
Molecular Formula
C17H11F3N4O2
Molecular Weight
360.29
References & Citations
[1]Lu Z, et al. Computational design of CDK1 inhibitors with enhanced target affinity and drug-likeness using deep-learning framework. Heliyon. 2024 Nov 14;10 (22) :e40345.|[2]Ogbodo UC, et al. Computational identification of potential inhibitors targeting cdk1 in colorectal cancer. Front Chem. 2023 Nov 30;11:1264808.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK1

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