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IHCH-7086

CAT: 0804-HY-169841-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-169841-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IHCH-7086 is a β-arrestin-biased 5-HT2A serotonin receptor agonist (Ki: 12.59 nM) . IHCH-7086 recruits β-arrestin through activation of 5-HT2A receptors, thereby removing hallucinogenic activity. IHCH-7086 improves depression-like behavior in mice without hallucinogenic effects[1][2].
CAS Number
[2957888-70-7]
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
98.96
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN1C2=C3C([C@@]4([H])[C@@](CCN(C4)CCCC5=C(C=CC=C5)OC)([H])N3CC1)=CC=C2
Molecular Formula
C24H31N3O
Molecular Weight
377.52
References & Citations
[1]Yin YN, Gao TM. Non-hallucinogenic Psychedelic Analog Design: A Promising Direction for Depression Treatment. Neurosci Bull. 2023 Jan;39 (1) :170-172.|[2]Cao D, et al. Structure-based discovery of nonhallucinogenic psychedelic analogs. Science. 2022 Jan 28;375 (6579) :403-411.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor

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