Epibatidine

• Description :

  Epibatidine is a α7nACh agonist with a Kd of 100 nM. Epibatidine can be used in the study of Alzheimer's, Parkinson's and schizophrenia[1].

• CAS Number :

  [140111-52-0]

• UNSPSC :

  12352005

• Target :

  NAChR

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Smiles :

  ClC1=NC=C([C@@H]2[C@]3([H])N[C@](CC3)([H])C2)C=C1

• Molecular Formula :

  C11H13ClN2

• Molecular Weight :

  208.69

• References & Citations :

  [1]Thompson AJ, et al. The binding orientation of epibatidine at α7 nACh receptors. Neuropharmacology. 2017 Apr;116:421-428. doi: 10.1016/j.neuropharm.2017.01.008. Epub 2017 Jan 12.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1