RAD51-IN-9

• Description:

  RAD51-IN-9 (Compound 3a) is a RAD51 inhibitor that can inhibit the binding of RAD51 to ssDNA with an IC50 of 17.85 μM. RAD51-IN-9 has a LD50 against HEK293 cells of 40.21 μM. RAD51-IN-9 can sensitize cells to Mitomycin C (HY-13316) [1].

• UNSPSC:

  12352005

• Target:

  RAD51

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Others

• Smiles:

  O=C1C (Cl) =C (N2CCOCC2) C (N1C3=CC=CC=C3) =O

• Molecular Formula:

  C14H13ClN2O3

• Molecular Weight:

  292.72

• References & Citations:

  [1]Budke B, et al. An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity. J Med Chem. 2013 Jan 10;56 (1) :254-63.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  103056-35-5