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Quorum sensing-IN-9

CAT: 0804-HY-168948Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168948Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Quorum sensing-IN-9 (Compound 7d) inhibits quorum sensing in Pseudomonas aeruginosa by binding PqsR proteins. Quorum sensing-IN-9 inhibits the expression of quorum sensing systems related genes lasB, rhlA and pqsA, blocks the generation of virulence factors elastase, pyocyanin and rhamnolipid. Quorum sensing-IN-9 destorys the motility of P. aeruginosa, inhibits the biofilm formation, decreasing the virulence and pathogenicity of P. aeruginosa. Quorum sensing-IN-9 exhibits anti-infectious activity in Galleria mellonella larval model[1].
CAS Number
3063543-24-5
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
OC1=CC=C(SSCC=C)C=C1
Molecular Formula
C9H10OS2
Molecular Weight
198.31
References & Citations
[1]Zhang ZS, et al., Design, Synthesis, and Biological Evaluation of Asymmetrical Disulfides Based on Garlic Extract as Pseudomonas aeruginosa pqs Quorum Sensing Inhibitors. J Agric Food Chem. 2025 Mar 12;73 (10) :5850-5859.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported