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ε-Rhodomycinone

CAT: 0804-HY-168779-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-168779-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ε-Rhodomycinone is a bacterial metabolite found in S. griseoruber. It is a precursor to Rhodomycin D, which is an intermediate in the bioconversion of ε-rhodomycinone to Daunorubicin and Doxorubicin (HY-15142R)[2][3].
CAS Number
21288-60-8
UNSPSC
12352005
Target
Bacterial; Drug Intermediate
Related Pathways
Anti-infection; Others
Field of Research
Cancer; Infection; Neurological Disease
Smiles
COC([C@@H]1C2=C([C@H](C[C@]1(O)CC)O)C(O)=C3C(C(C4=CC=CC(O)=C4C3=O)=O)=C2O)=O
Molecular Formula
C22H20O9
Molecular Weight
428.39
References & Citations
[1]Podojil M, et al. Production of rhodomycins in Streptomyces griseoruber 4620. Folia Microbiol (Praha) . 1980;25 (6) :464-6.|[2]Olano C, et al. A two-plasmid system for the glycosylation of polyketide antibiotics: bioconversion of epsilon-rhodomycinone to rhodomycin D. Chem Biol. 1999 Dec;6 (12) :845-55.|[3]Dickens ML, et al. In vivo and in vitro bioconversion of epsilon-rhodomycinone glycoside to doxorubicin: functions of DauP, DauK, and DoxA. J Bacteriol. 1997 Apr;179 (8) :2641-50.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
WAA28860-01ε-Rhodomycinone

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