Gepotidacin (Standard)

• Description :

  Gepotidacin (Standard) is the analytical standard of Gepotidacin. This product is intended for research and analytical applications. Gepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor.

• CAS Number :

  [1075236-89-3]

• Product Name Alternative :

  GSK2140944 (Standard)

• UNSPSC :

  12352005

• Target :

  Antibiotic; Bacterial; Reference Standards; Topoisomerase

• Related Pathways :

  Anti-infection; Cell Cycle/DNA Damage; Others

• Field of Research :

  Infection

• Smiles :

  O=C(C=NC(C=C1)=C23)N3[C@H](CN4CCC(NCC5=CC(CCCO6)=C6C=N5)CC4)CN2C1=O

• Molecular Formula :

  C24H28N6O3

• Molecular Weight :

  448.52

• References & Citations :

  [1]Farrell DJ, et al. In Vitro Activity of Gepotidacin (GSK2140944) against Neisseria gonorrhoeae. Antimicrob Agents Chemother. 2017 Feb 23;61 (3) .|[2]Biedenbach DJ, et al. In Vitro Activity of Gepotidacin, a Novel Triazaacenaphthylene Bacterial Topoisomerase Inhibitor, against a Broad Spectrum of Bacterial Pathogens. Antimicrob Agents Chemother. 2016 Jan 4;60 (3) :1918-23.|[3]O'Riordan W, et al. Efficacy, Safety, and Tolerability of Gepotidacin (GSK2140944) in the Treatment of Patients with Suspected or Confirmed Gram-Positive Acute Bacterial Skin and Skin Structure Infections. Antimicrob Agents Chemother. 2017 May 24;61 (6) .|[4]So W, et al. Pharmacodynamic Profile of GSK2140944 against Methicillin-Resistant Staphylococcus aureus in a Murine Lung Infection Model. Antimicrob Agents Chemother. 2015 Aug;59 (8) :4956-61.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards