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Beraprost-d3

CAT: 0804-HY-166363SSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-166363SSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Beraprost-d3 (TRK-100-d3) is deuterium labeled (Rac) -Beraprost. (Rac) -Beraprost ((Rac) -ML 1229) is an orally active prostacyclin analog that inhibits the release of Ca2+ from intracellular storage sites by binding to prostacyclin membrane receptors (Prostaglandin Receptor), leading to relaxation of smooth muscle cells and vasodilation. Beraprost has vasodilatory, antiplatelet, and cytoprotective effects, making it promising for research in the field of cardiovascular diseases, such as thromboangiitis obliterans and atherosclerosis[1].
Product Name Alternative
TRK-100-d3; ML 1129-d3
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Prostaglandin Receptor
Related Pathways
GPCR/G Protein; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
O=C(CCCC1=CC=CC2=C1OC3CC(C(C23)/C=C/C(C(CC#CC)C([2H])([2H])[2H])O)O)O
Molecular Formula
C24H27D3O5
Molecular Weight
401.51
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Li S, et al. Beraprost sodium mitigates renal interstitial fibrosis through repairing renal microvessels. J Mol Med (Berl) . 2019 Jun;97 (6) :777-791.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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