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Toborinone

CAT: 0804-HY-165436Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-165436Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Toborinone is an inotropic agent. Toborinone increases cAMP and intracellular calcium levels through inhibiting PDE. Toborinone inhibits thrombin-induced platelet aggregation with an IC50 of 9.7 μM[1][2].
CAS Number
143343-83-3
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
COC1=C(C=CC(CNCC(COC2=CC=C3C(C=CC(N3)=O)=C2)O)=C1)OC
Molecular Formula
C21H24N2O5
Molecular Weight
384.43
References & Citations
[1]MacGowan G. A. (2000) . Clinical overview of the novel inotropic agent toborinone. Expert opinion on investigational drugs, 9 (5), 1109-1117.|[2]Kageyama, K., et al., (2004) . Toborinone and olprinone, phosphodiesterase III inhibitors, inhibit human platelet aggregation due to the inhibition of both calcium release from intracellular stores and calcium entry. Journal of anesthesia, 18 (2), 107-112.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
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