Temoporfin (Standard)

• Description :

  Temoporfin (Standard) is the analytical standard of Temoporfin. This product is intended for research and analytical applications. Temoporfin (m-THPC), a reduced porphyrin, is a potent second-generation photosensitizer. Temoporfin can be used in the research of photodynamic therapy (PDT) for head and neck cancers[1][2][3].

• CAS Number :

  [122341-38-2]

• UNSPSC :

  12352100

• Target :

  Reactive Oxygen Species (ROS) ; Reference Standards

• Related Pathways :

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

• Field of Research :

  Cancer

• Smiles :

  OC1=CC=CC(/C2=C3CCC(/C(C4=CC(O)=CC=C4)=C5C=C/C(N/5)=C(C6=CC(O)=CC=C6)/C(C=C/7)=NC7=C(C8=CC(O)=CC=C8)/C9=CC=C2N9)=N\3)=C1

• Molecular Formula :

  C44H32N4O4

• Molecular Weight :

  680.75

• References & Citations :

  [1]Senge MO, et, al. Temoporfin (Foscan®, 5,10,15,20-tetra (m-hydroxyphenyl) chlorin) --a second-generation photosensitizer. Photochem Photobiol. 2011 Nov-Dec;87 (6) :1240-96.|[2]Rovers JP, et, al. Effective treatment of liver metastases with photodynamic therapy, using the second-generation photosensitizer meta-tetra (hydroxyphenyl) chlorin (mTHPC), in a rat model. Br J Cancer. 1999 Oct;81 (4) :600-8. |[3]Reshetov V, et, al. Photodynamic therapy with conventional and PEGylated liposomal formulations of mTHPC (temoporfin) : comparison of treatment efficacy and distribution characteristics in vivo. Int J Nanomedicine. 2013;8:3817-31.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards