Products for Research Use Only
RegisterLogin

CNDAC (hydrochloride) (Standard)

CAT: 0804-HY-16445BRSize: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-16445BRSize:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Dioscin (Standard) is the analytical standard of Dioscin. This product is intended for research and analytical applications. Dioscin (CCRIS 4123; Collettiside III) is a natural plant-derived steroidal saponin that has good anti-cancer activity against a variety of cancer cells. Dioscin causes DNA damage and induces apoptosis in HeLa and SiHa cells. Dioscin regulates ROS-mediated DNA damage and mitochondrial signaling pathways, exerting anticancer activity[1][2][3][4][5][6].
CAS Number
134665-72-8
UNSPSC
12352005
Target
Apoptosis; DNA/RNA Synthesis; Drug Metabolite; Nucleoside Antimetabolite/Analog; Reference Standards
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
O=C(N=C(N)C=C1)N1[C@H]2[C@@H](C#N)[C@H](O)[C@@H](CO)O2.Cl
Molecular Formula
C10H13ClN4O4
Molecular Weight
288.69
References & Citations
[1]Liu XJ, et al. Sapacitabine, the prodrug of CNDAC, is a nucleoside analog with a unique action mechanism of inducing DNA strand breaks. Chin J Cancer. 2012 Aug;31 (8) :373-80.|[2]Jagan S, et al. Bone Marrow and Peripheral Blood AML Cells Are Highly Sensitive to CNDAC, the Active Form of Sapacitabine. Adv Hematol. 2012;2012:727683.|[3]Serova M, et al. Antiproliferative effects of sapacitabine (CYC682), a novel 2'-deoxycytidine-derivative, in human cancer cells. Br J Cancer. 2007 Sep 3;97 (5) :628-36.|[4]Azuma A, et al. Nucleosides and nucleotides. 122. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine and its derivatives. A new class of nucleoside with a broad antitumor spectrum. J Med Chem. 1993 Dec 24;36 (26) :4183-9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-16445B-01CNDAC (hydrochloride)
HY-16445ACNDAC
HY-17386AR-01Rosiglitazone (hydrochloride) (Standard)
HY-17038AR-01Agomelatine (hydrochloride) (Standard)
HY-17034BR-01Medetomidine (hydrochloride) (Standard)
HY-15488AR-01A 438079 (hydrochloride) (Standard)
HY-15180R-01Buparlisib (Hydrochloride) (Standard)
HY-14561ARIdazoxan (hydrochloride) (Standard)
HY-14338AR-01Idalopirdine (hydrochloride) (Standard)
HY-13715AR-01Norepinephrine (hydrochloride) (Standard)

Alternative Products

CatalogName
T13621-01CNDAC hydrochloride
CS-ET-00040Trazodone hydrochloride impurity standard (591)
GTR19204391-01CNDAC
abx098967-01Standard
300563Ligustrazine Hydrochloride (Chuanxiongzine hydrochloride)
D3190-91GDeoxynojirimycin Hydrochloride (DNJ Hydrochloride)
ST-08004-02Ascorbic Acid Standard + Gallic Acid Standard + TROLOX Standard + BRS Electrolyte
RE21029ARAb Standard A (Standard 0) 20 ml
ST-80004-01Ascorbic Acid Standard + Gallic Acid Standard + TROLOX Standard for biological samples
OR1043462-01Hydrochloride

Popular Products