AFB1-FapyGua

• Description:

  AFB1-FapyGua is a major Guanine (HY-Y1055) adduct in cells and AFB1-N7-Gua derivative. AFB1-FapyGua exhibits a high mutagenic effect[1][2].

• UNSPSC:

  12352005

• Target:

  Drug Derivative; Nucleoside Antimetabolite/Analog

• Related Pathways:

  Cell Cycle/DNA Damage; Others

• Field of Research:

  Others

• Smiles:

  O[C@@H]1[C@@]2([H])C3=C(O[C@@]2([H])O[C@H]1N(C4=C(NC(N)=NC4=O)N)C=O)C=C(OC)C(C5=C6C(CC5)=O)=C3OC6=O

• Molecular Formula:

  C22H19N5O9

• Molecular Weight:

  497.41

• References & Citations:

  [1]Mohamed AA, et al. When less is more: The association between the expression of polymorphic CYPs and AFB1-induced HCC. Eur J Clin Invest. 2024 Dec;54 (12) :e14297. |[2]Yan S, et al. Inspiring basic and applied research in genome integrity mechanisms: Dedication to Samuel H. Wilson. Environ Mol Mutagen. 2024 Apr;65 Suppl 1 (Suppl 1) :4-8.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [65386-83-6]