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AFB1-FapyGua

CAT: 0804-HY-164172Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-164172Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AFB1-FapyGua is a major Guanine adduct in cells and AFB1-N7-Gua derivative. AFB1-FapyGua exhibits a high mutagenic effect[1][2].
CAS Number
65386-83-6
UNSPSC
12352005
Target
Drug Derivative; Nucleoside Antimetabolite/Analog
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Others
Smiles
O[C@@H]1[C@@]2([H])C3=C(O[C@@]2([H])O[C@H]1N(C4=C(NC(N)=NC4=O)N)C=O)C=C(OC)C(C5=C6C(CC5)=O)=C3OC6=O
Molecular Formula
C22H19N5O9
Molecular Weight
497.41
References & Citations
[1]Mohamed AA, et al. When less is more: The association between the expression of polymorphic CYPs and AFB1-induced HCC. Eur J Clin Invest. 2024 Dec;54 (12) :e14297. |[2]Yan S, et al. Inspiring basic and applied research in genome integrity mechanisms: Dedication to Samuel H. Wilson. Environ Mol Mutagen. 2024 Apr;65 Suppl 1 (Suppl 1) :4-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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