Products for Research Use Only
RegisterLogin

QI-18

CAT: 0804-HY-159934Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-159934Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
QI-18 is a fibroblast activation protein (FAP) inhibitor with the IC50 of 0.50 nM, which is a 6.5-fold increase in potency over that of UAMC-1110. QI-18 can be used to synthesize high tumor selectivity and high dose radiotracers for the diagnosis and treatment of tumors[1].
CAS Number
3093894-38-0
UNSPSC
12352005
Target
FAP
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Smiles
OC(CNC([C@H](CC1=CC=C(C#N)C=C1)NC(COC2=CC=C(N=CC=C3C(NCC(N4CC(F)(F)C[C@H]4C#N)=O)=O)C3=C2)=O)=O)=O
Molecular Formula
C31H27F2N7O7
Molecular Weight
647.59
References & Citations
[1]Qiu X, et al. Rational modifications on N- (4-quinolinoyl) -Gly-2-cyanopyrrolidine to develop fibroblast activation protein-targeted radioligands with improved affinity and tumor uptake. Eur J Med Chem. 2025 Jan 5;281:117011.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-W011222S1-011-Bromooctadecane-18,18,18-d3
HY-N11142Gb3 (18:1/18:0)
HY-143203-0118:0-18:2 PE
HY-W105737-0118-Methoxy-18-oxooctadecanoic acid
HY-CE0053718-CoA-18-oxo-dinor-LTB4
HY-148978-0118:0,18:1 PS (sodium)
HY-W72530918:0-18:1 PA (sodium)
HY-157618-0118:0-18:1 PG (sodium)
HY-N11142SGb3-d7 (18:1/18:0)
HY-170458-0118:0-18:2 PG (sodium)

Alternative Products

CatalogName
T206674-01QI-18
TRC-S686499-5MGOctadecanoic-18,18,18-d3 Acid
sc-236934Stearic acid-18,18,18-d3
B6873671-Bromooctadecane-18,18,18-d3
T886456Glyceryl Tri(octadecanoate-18,18,18-d3)
MBS343012-01Cytokeratin-18 (CK-18)
MO-C40094A-01Interleukin-18 (IL-18)
GTR19194971CP-18 F-18
MM-1009-02Cytokeratin 18 (CK 18)
228184Cytokeratin 18 (Keratin 18)

Popular Products