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Penicinoline

CAT: 0804-HY-158721Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-158721Size:1 Each
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Description
Penicinoline (Marinamide) (Compound 1), a pyrrolyl 4-quinolinone alkaloid, is a microbial secondary metabolite. Penicinoline can be isolated from endophytic fungus Penicillium sp. Penicinoline has antimalarial activity against Chloroquine sensitive strain (pf3d7) and against Chloroquine resistant strain (pfDd2) of plasmodium falciparum. Penicinoline also has strong insecticidal activity against Aphis gossypii and selective anticancer effect with significant cytotoxicity for 95-D and HepG2 cells[1][2].
CAS Number
1214268-60-6
Product Name Alternative
Marinamide
UNSPSC
12352005
Target
Endogenous Metabolite; Parasite
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Cancer; Infection
Smiles
O=C(C1=C(C2=CC=CN2)NC3=C(C=CC=C3)C1=O)O
Molecular Formula
C14H10N2O3
Molecular Weight
254.24
References & Citations
[1]Shao CL, et al. Penicinoline, a new pyrrolyl 4-quinolinone alkaloid with an unprecedented ring system from an endophytic fungus Penicillium sp. Bioorg Med Chem Lett. 2010 Jun 1;20 (11) :3284-6.|[2]Naveen B, et al. Total synthesis of penicinoline E, marinamide, methyl marinamide and their antimalarial activity[J]. ChemistrySelect, 2017, 2 (11) : 3256-3261.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

Alternative Products

CatalogName
P147-5MGPenicinoline

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