IPA-3 (Standard)

CAT: 0804-HY-15663R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-15663R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IPA-3 (Standard) is the analytical standard of IPA-3. This product is intended for research and analytical applications. IPA-3 is a selective non-ATP competitive PAK1 inhibitor with IC50 of 2.5 μM, and shows no inhibition to group II PAKs (PAKs 4-6) .
CAS Number
[42521-82-4]
UNSPSC
12352100
Target
PAK; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Others
Field of Research
Cancer
Smiles
OC1=CC=C2C=CC=CC2=C1SSC3=C4C=CC=CC4=CC=C3O
Molecular Formula
C20H14O2S2
Molecular Weight
350.45
References & Citations
[1]Viaud J, et al. An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently. Mol Cancer Ther. 2009 Sep;8 (9) :2559-65.|[2]Flaiz C, et al. PAK kinase regulates Rac GTPase and is a potential target in human schwannomas. Exp Neurol. 2009 Jul;218 (1) :137-44.|[3]Deacon SW, et al. An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase. Chem Biol. 2008 Apr;15 (4) :322-31
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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