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R419

CAT: 0804-HY-153156Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-153156Size:1 Each
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Description
R419 is a Complex I inhibitor. R419 has anti-cancer activity against liver cancer[1].
CAS Number
1356629-00-9
UNSPSC
12352005
Target
Oxidative Phosphorylation
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
N#CC1=CC=C(CN2CCC(CC2)NC(C3=CN=C(C(N4CCC(CC4)C(C5=CC=C(C=C5)OC)=O)=O)C=C3)=O)C=C1
Molecular Formula
C33H35N5O4
Molecular Weight
565.66
References & Citations
[1]Huang Y, et al. Synthesis and biological evaluation of Complex I inhibitor R419 and its derivatives as anticancer agents in HepG2 cells. Bioorg Med Chem Lett. 2018 Sep 15;28 (17) :2957-2960.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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