Products for Research Use Only
RegisterLogin

BIHC

CAT: 0804-HY-152169-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-152169-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
BIHC is a TNF blocker with anti-inflammatory activity. BIHC can significantly inhibit the proliferation of hepatocellular carcinoma (HCC) cells and exhibits potent cytotoxicity against the HepG2 cell line, capable of inducing cell apoptosis , while demonstrating relatively low toxicity towards normal hepatocytes. Additionally, BIHC can be used for research on inflammatory bowel disease (IBD) [1].
CAS Number
1642826-40-1
UNSPSC
12352005
Target
Apoptosis; Bcl-2 Family; IFNAR; Interleukin Related; NF-κB; TNF Receptor
Related Pathways
Apoptosis; Immunology/Inflammation; NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Inflammation/Immunology
Purity
98.0
Smiles
O=C1OC2=C(C(O)=C1C(C3=C(O)C4=C(C=CC=C4)OC3=O)C5=C(Cl)N=C(CCCC)N5)C=CC=C2
Molecular Formula
C26H21ClN2O6
Molecular Weight
492.91
References & Citations
[1]Keerthy H K, Mohan C D, Siveen K S, et al. Novel synthetic biscoumarins target tumor necrosis factor-α in hepatocellular carcinoma in vitro and in vivo[J]. Journal of Biological Chemistry, 2014, 289 (46) : 31879-31890.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
T204826-01BIHC

Popular Products