Products for Research Use Only
RegisterLogin

Avosentan (Standard)

CAT: 0804-HY-15195R-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-15195R-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Avosentan (Standard) is the analytical standard of Avosentan. This product is intended for research and analytical applications. Avosentan is an orally active endothelin (ETA) receptor antagonist. Avosentan can block the ETA receptor, thereby reducing vascular contraction, and exerting a renal protective effect. Avosentan inhibits vascular contraction caused by ET-1 and alleviates the reduction in retinal and optic nerve head blood flow induced by it, lowering intraocular pressure in the glaucoma monkey model. Avosentan non-specifically blocks ETB receptors at high doses, inhibiting ETB-mediated diuresis and natriuresis, and may cause fluid retention. Avosentan can be used to reduce proteinuria with diabetic nephropathy, but induces significant fluid overload and congestive heart failure.
CAS Number
290815-26-8
Product Name Alternative
Ro 67-0565 (Standard) ; SPP-301 (Standard)
UNSPSC
12352100
Target
Endothelin Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Others
Field of Research
Cardiovascular Disease; Endocrinology
Smiles
COC1=C(OC(C(NS(C2=NC=C(C=C2)C)(=O)=O)=NC(C3=CC=NC=C3)=N4)=C4OC)C=CC=C1
Molecular Formula
C23H21N5O5S
Molecular Weight
479.51
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
No Development Reported

Related Products

CatalogName
HY-15195-01Avosentan
HY-P2274RArgifin (Standard)
HY-N9362REmodinanthrone (Standard)
HY-N7948RIsomaltotetraose (Standard)
HY-N7640RDeoxylimonin (Standard)
HY-N7617RToralactone (Standard)
HY-N7541RAntrodin A (Standard)
HY-N6739RBeauvericin (Standard)
HY-N6687RCalcimycin (Standard)
HY-N3373RLoganetin (Standard)

Alternative Products

CatalogName
QLA81526-01Avosentan
A11301-50Avosentan 50mg
MBS386692-01Avosentan (SPP301)
A11301-25Avosentan 25mg
TRC-A794712-25MGAvosentan-d3
A11301-10Avosentan 10mg
A11301-5Avosentan 5mg
A11301-100Avosentan (SPP301) 100mg
A11301-1Avosentan (SPP301) 1mg
A11301-10mM-DAvosentan (SPP301) 10mM * 1mL in DMSO

Popular Products