Brigatinib A

• Description :

  Brigatinib A is an GID4 ligand. Brigatinib A can be used for synthesizing PROTAC BCR-ABL Degrader-2 (HY-174368) [1].

• UNSPSC :

  12352005

• Target :

  Ligands for E3 Ligase

• Related Pathways :

  PROTAC

• Field of Research :

  Cancer

• Smiles :

  COC1=CC(N2CCNCC2)=CC=C1NC3=NC=C(C(NC4=CC=CC=C4P(C)(C)=O)=N3)Cl

• Molecular Formula :

  C23H28ClN6O2P

• Molecular Weight :

  486.93

• References & Citations :

  [1]Zhang J, et al. Linker-free PROTACs efficiently induce the degradation of oncoproteins. Nat Commun. 2025 May 23;16 (1) :4794.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1197958-90-9]