Brigatinib A

• Description:

  Brigatinib A is an GID4 ligand. Brigatinib A can be used for synthesizing PROTAC BCR-ABL Degrader-2 (HY-174368) [1].

• UNSPSC:

  12352005

• Target:

  Ligands for E3 Ligase

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Smiles:

  COC1=CC(N2CCNCC2)=CC=C1NC3=NC=C(C(NC4=CC=CC=C4P(C)(C)=O)=N3)Cl

• Molecular Formula:

  C23H28ClN6O2P

• Molecular Weight:

  486.93

• References & Citations:

  [1]Zhang J, et al. Linker-free PROTACs efficiently induce the degradation of oncoproteins. Nat Commun. 2025 May 23;16 (1) :4794.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1197958-90-9