Tazolol

CAT: 0804-HY-149796Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-149796Size:1 Each

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Description

Tazolol is a specific β-adrenergic antagonist (IC50: 700 nM for (-) isoproterenol-elicited accumulation of cyclic AMP in rat cortical slices) . Tazolol produces a significant and sustained increase in cardiac output and stroke volume. Tazolol can be used in the research of heart failure[1][2].

CAS Number

39832-48-9

UNSPSC

12352005

Target

Adrenergic Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Cardiovascular Disease

Smiles

OC(CNC(C)C)COC1=NC=CS1

Molecular Formula

C9H16N2O2S

Molecular Weight

216.30

References & Citations

[1]Skolnick, et al. Blockade of central beta-adrenergic receptors by tazolol (1-isopropylamino-3- (2-thiazoloxy) -2-propanol) . Life Sci. 1977 Dec 1;21 (11) :1655-63. |[2]Buckley HT, et al. Circulatory effects of tazolol in experimental myocardial infarction. Am J Cardiol. 1975 May;35 (5) :619-25.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

β adrenergic receptor

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Tazolol

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