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Ena15

CAT: 0804-HY-149145-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-149145-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ena15 is an ALKBH5 inhibitor. Ena15 enhances the demethylase activity of FTO. Ena15 increases m6A RNA level, and stabilizes FOXM1 mRNA. Ena15 suppresses the growth activity of glioblastoma multiforme[1].
CAS Number
956935-02-7
UNSPSC
12352005
Target
Anaplastic lymphoma kinase (ALK) ; Fat Mass and Obesity-associated Protein (FTO)
Related Pathways
Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Purity
99.0
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C(N(CC1=CC=C(CC)C=C1)CC2=CC=CN=C2)C3=C(C)N(CC4=CC=CC=C4)N=C3C
Molecular Formula
C28H30N4O
Molecular Weight
438.56
References & Citations
[1]Takahashi H, et al. Discovery of two novel ALKBH5 selective inhibitors that exhibit uncompetitive or competitive type and suppress the growth activity of glioblastoma multiforme. Chem Biol Drug Des. 2022 Jul;100 (1) :1-12.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
GTR19249463-01Ena15

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