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Picoberin

CAT: 0804-HY-148637Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-148637Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Picoberin is a low picomolar inhibitor of Hedgehog-induced osteoblast differentiation. Picoberin is a potent aryl hydrocarbon receptor (AhR) agonist. Picoberin inhibits Wnt3A-induced osteoblast differentiation of C3H10T1/2 cells. Picoberin can upregulate genes encoding phase I and II metabolic enzymes[1].
CAS Number
3034663-23-2
UNSPSC
12352005
Target
Aryl Hydrocarbon Receptor
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Others
Smiles
O=C1N2[C@@H](CC3=CC(Cl)=C(C=C31)Br)C4=C(CC2)C=CC=C4
Molecular Formula
C17H13BrClNO
Molecular Weight
362.65
References & Citations
[1]Flegel, J., et al., (2022) . The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation. Journal of medicinal chemistry, 65 (24), 16268-16289.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
GTR19274418-01Picoberin

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