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Cobiprostone

CAT: 0804-HY-14764Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-14764Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cobiprostone (SPI 8811) is a type-2 chloride channel activator. Cobiprostone protects against Indomethacin -induced depolarization of mitochondrial membrane potential and reverses the loss of mitochondrial membrane potential. Cobiprostone protects against NSAID-induced cellular damage[1].
CAS Number
333963-42-1
Product Name Alternative
SPI 8811
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Chloride Channel; Mitochondrial Metabolism
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C(O)CCCCCC[C@H]([C@]1([H])[C@]2([H])O[C@@](O)(C(F)(F)C[C@@H](C)CC)CC1)C(C2)=O
Molecular Formula
C21H34F2O5
Molecular Weight
404.49
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Cuppoletti J, et al. Cobiprostone Is a Type-2 Chloride Channel Activator That Protects Against NSAID-Induced Cellular Damage: 126. Official journal of the American College of Gastroenterology| ACG, 2007, 102: S163-S164.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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GTR19274134-01Cobiprostone

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