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Refametinib (Standard)

CAT: 0804-HY-14691R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14691R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Refametinib (Standard) is the analytical standard of Refametinib. This product is intended for research and analytical applications. Refametinib (BAY 869766; RDEA119) is an orally available, potent, non-ATP-competitive, selective, allosteric MEK1/MEK2 inhibitor with IC50s of 19 nM and 47 nM, respectively.
CAS Number
923032-37-5
UNSPSC
12352100
Target
MEK; Reference Standards
Related Pathways
MAPK/ERK Pathway; Others
Field of Research
Cancer
Smiles
O=S(C1(C[C@H](O)CO)CC1)(NC(C(NC(C(F)=C2)=CC=C2I)=C3F)=C(OC)C=C3F)=O
Molecular Formula
C19H20F3IN2O5S
Molecular Weight
572.34
References & Citations
[1]Iverson C, et al. RDEA119/BAY 869766: a potent, selective, allosteric inhibitor of MEK1/2 for the treatment of cancer. Cancer Res. 2009 Sep 1;69 (17) :6839-47.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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