Products for Research Use Only
RegisterLogin

Escitalopram (Standard)

CAT: 0804-HY-14258R-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-14258R-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Escitalopram (Standard) is the analytical standard of Escitalopram. This product is intended for research and analytical applications. Escitalopram ((S) -Citalopram), the S-enantiomer of racemic Citalopram, is a selective serotonin reuptake inhibitor (SSRI) with a Ki of 0.89 nM. Escitalopram has ～30 fold higher binding affinity than its R (-) -enantiomer and shows selectivity over both dopamine transporter (DAT) and norepinephrine transporter (NET) . Escitalopram is an antidepressant for the research of major depression[1][2].
CAS Number
128196-01-0
UNSPSC
12352100
Target
Reference Standards; Serotonin Transporter
Related Pathways
Neuronal Signaling; Others
Field of Research
Neurological Disease; Cancer
Smiles
FC1=CC=C([C@@]2(CCCN(C)C)C(C=CC(C#N)=C3)=C3CO2)C=C1
Molecular Formula
C20H21FN2O
Molecular Weight
324.39
References & Citations
[1]Zhang, P., et al., Structure-activity relationships for a novel series of citalopram (1- (3- (dimethylamino) propyl) -1- (4-fluorophenyl) -1,3-dihydroisobenzofuran-5-carbon itrile) analogues at monoamine transporters. J Med Chem, 2010. 53 (16) : p. 6112-21.|[2]Pastoor, D. and J. Gobburu, Clinical pharmacology review of escitalopram for the treatment of depression. Expert Opin Drug Metab Toxicol, 2014. 10 (1) : p. 121-8.|[3]Wu C , et al. Escitalopram alleviates stress-induced Alzheimer's disease-like tau pathologies and cognitive deficits by reducing hypothalamic-pituitary-adrenal axis reactivity and insulin/GSK-3β signal pathway activity. Neurobiol Aging. 2018;67:137-147.|[4]Cirrito JR, et al. Effect of escitalopram on Aβ levels and plaque load in an Alzheimer mouse model. Neurology. 2020;95 (19) :e2666-e2674.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-14258AR-01Escitalopram (oxalate) (Standard)
HY-14258-01Escitalopram
HY-14258A-01Escitalopram (oxalate)
HY-14258ASEscitalopram-d6 (oxalate)
HY-14258AS1-01Escitalopram-d4 (oxalate)
HY-P2274RArgifin (Standard)
HY-N9362REmodinanthrone (Standard)
HY-N7948RIsomaltotetraose (Standard)
HY-N7640RDeoxylimonin (Standard)
HY-N7617RToralactone (Standard)

Alternative Products

CatalogName
B1183-50Escitalopram

Popular Products