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Methyltetrazine-PEG5-triethoxysilane

CAT: 0804-HY-141283-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-141283-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Methyltetrazine-PEG5-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Methyltetrazine-PEG5-triethoxysilane is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
CAS Number
2353410-01-0
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
PROTAC Linkers
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
O=C(NCCC[Si](OCC)(OCC)OCC)CCOCCOCCOCCOCCOC1=CC=C(C2=NN=C(C)N=N2)C=C1
Molecular Formula
C29H49N5O9Si
Molecular Weight
639.81
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers

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