25 (S) -27-Hydroxy cholesterol

• Description:

  25 (S) -27-Hydroxy cholesterol is a metabolite of CYP27A1 mediated cholesterol hydroxylation. 25 (S) -27-Hydroxy cholesterol inhibits melanoma cell proliferation[1].

• UNSPSC:

  12352211

• Target:

  LXR

• Related Pathways:

  Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Smiles:

  C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC[C@H](C)CO)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=CC3)C

• Molecular Formula:

  C27H46O2

• Molecular Weight:

  402.65

• References & Citations:

  [1]Tuckey RC, et al. CYP27A1 acts on the pre-vitamin D3 photoproduct, lumisterol, producing biologically active hydroxy-metabolites. J Steroid Biochem Mol Biol. 2018 Jul;181:1-10.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  56845-83-1