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25 (S) -27-Hydroxy cholesterol

CAT: 0804-HY-139067-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-139067-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
25 (S) -27-Hydroxy cholesterol is a metabolite of CYP27A1 mediated cholesterol hydroxylation. 25 (S) -27-Hydroxy cholesterol inhibits melanoma cell proliferation[1].
CAS Number
56845-83-1
UNSPSC
12352211
Target
LXR
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC[C@H](C)CO)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=CC3)C
Molecular Formula
C27H46O2
Molecular Weight
402.65
References & Citations
[1]Tuckey RC, et al. CYP27A1 acts on the pre-vitamin D3 photoproduct, lumisterol, producing biologically active hydroxy-metabolites. J Steroid Biochem Mol Biol. 2018 Jul;181:1-10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported