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Tetraacetylphytosphingosine

CAT: 0804-HY-138875-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-138875-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tetraacetylphytosphingosine is a sphingolipid metabolite produced by phytosphingosine acetylation. Tetraacetylphytosphingosine exerts its inhibitory action on angiogenesis through the inhibition of MAPK activation and intracellular calcium increase[1]. Tetraacetylphytosphingosine induces apoptosis in HaCaT cells[2].
CAS Number
13018-48-9
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; p38 MAPK
Related Pathways
Apoptosis; MAPK/ERK Pathway
Field of Research
Cancer; Cardiovascular Disease
Purity
99.90
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
CCCCCCCCCCCCCC[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](NC(C)=O)COC(C)=O
Molecular Formula
C26H47NO7
Molecular Weight
485.65
Precautions
H302, H315, H319, H335
References & Citations
[1]Yoo Bin Kwon, et al. Anti-angiogenic effect of tetraacetyl-phytosphingosine. Exp Dermatol. 2007 Apr;16 (4) :311-7. |[2]H J Kim, et al. Potentiation of UVB-induced apoptosis by novel phytosphingosine derivative, tetraacetyl phytosphingosine in HaCaT cell and mouse skin. Apoptosis. 2004 Jul;9 (4) :449-56.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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CatalogName
FT180755-01Tetraacetylphytosphingosine

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