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Zelpolib

CAT: 0804-HY-137921Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-137921Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Zelpolib is a non-competitive Pol δ inhibitor. Zelpolib shows robust inhibition of Pol δ activity against dTTP with a Ki of 4.3 μM. Zelpolib inhibits cellular DNA replication. Zelpolib shows antiproliferative properties[1].
CAS Number
701932-26-5
UNSPSC
12352005
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C(OC)C=1C=C(SC1NC(=S)NNC(=O)CCC2=CC=C(O)C(O)=C2)C=3C=CC=CC3
Molecular Formula
C22H21N3O5S2
Molecular Weight
471.55
References & Citations
[1]Mishra B, et al. Discovery of a novel DNA polymerase inhibitor and characterization of its antiproliferative properties. Cancer Biol Ther. 2019;20 (4) :474-486.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T68837-01Zelpolib

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