Mergocriptine

• Description :

  Mergocriptine (CBM36-733) is a dopamine receptor agonist and SARS-CoV-2 Mpro ligand. Mergocriptine regulates ambulatory activity[1][2].

• CAS Number :

  [81968-16-3]

• Product Name Alternative :

  CBM36-733

• UNSPSC :

  12352005

• Target :

  Dopamine Receptor; SARS-CoV; Virus Protease

• Related Pathways :

  Anti-infection; GPCR/G Protein; Neuronal Signaling

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection; Neurological Disease

• Smiles :

  O[C@@]([C@@](CCC1)([H])N1C2=O)(O[C@](C(C)C)3NC([C@@H](CN4C)C=C([C@@]4([H])C5)C6=CC=CC(N7)=C6C5=C7C)=O)N([C@H]2CC(C)C)C3=O

• Molecular Formula :

  C33H43N5O5

• Molecular Weight :

  589.73

• References & Citations :

  [1]Piplani S, et al. Computational Repurposing of Drugs and Natural Products Against SARS-CoV-2 Main Protease (Mpro) as Potential COVID-19 Therapies. Front Mol Biosci. 2022 Mar 14;9:781039.|[2]Kuribara H, et al. Behavioral study on mergocriptine (CBM36-733) by ambulatory activity in mice: repeated administration and interaction with methamphetamine. Jpn J Pharmacol. 1990 Oct;54 (2) :163-70.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported