Dibutyl phosphate

• Description :

  Dibutyl phosphate (DBUP) is a urinary metabolite of organophosphate esters (OPEs) . Dibutyl phosphate is positively correlated with an increased risk of sarcopenia[1][2][3].

• CAS Number :

  [107-66-4]

• Product Name Alternative :

  DBUP

• UNSPSC :

  12352211

• Hazard Statement :

  H314, H351

• Target :

  Drug Metabolite

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Metabolic Disease

• Purity :

  97.0

• Solubility :

  DMSO : 200 mg/mL (ultrasonic)

• Smiles :

  O=P(OCCCC)(O)OCCCC

• Molecular Formula :

  C8H19O4P

• Molecular Weight :

  210.21

• Precautions :

  H314, H351

• References & Citations :

  [1]Wu YJ, et al. Dipeptidyl peptidase-4 inhibitor, vildagliptin, inhibits pancreatic beta cell apoptosis in associationwith its effects suppressing endoplasmic reticulum stress in db/db mice. Metabolism. 2015 Feb;64 (2) :226-35.|[2]Villhauer EB, et al. 1-[[ (3-hydroxy-1-adamantyl) amino]acetyl]-2-cyano- (S) -pyrrolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties. J Med Chem. 2003 Jun 19;46 (13) :2774-89.|[3]Nan W, Peng Z, Yi T, Ouyang M, Hu J. Association between exposure to organophosphate esters metabolites and sarcopenia prevalence: A cross-sectional study using NHANES data. Ecotoxicol Environ Saf. 2024 Oct 15;285:117041.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound2

• Clinical Information :

  No Development Reported