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Ascomycin (Standard)

CAT: 0804-HY-13557R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13557R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ascomycin (Standard) is the analytical standard of Ascomycin. This product is intended for research and analytical applications. Ascomycin (Immunomycin; FR-900520; FK520) is an ethyl analog of Tacrolimus (FK506) with strong immunosuppressant properties. Ascomycin is also a macrocyclic polyketide antibiotic with multiple biological activities such as anti-malarial, anti-fungal and anti-spasmodic. Ascomycin prevents graft rejection and has potential for varying skin ailments research[1][2].
CAS Number
104987-12-4
Product Name Alternative
Immunomycin (Standard) ; FR-900520 (Standard) ; FK520 (Standard)
UNSPSC
12352005
Target
Antibiotic; FKBP; Fungal; Parasite; Reference Standards
Related Pathways
Anti-infection; Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation; Others
Field of Research
Infection; Inflammation/Immunology; Neurological Disease
Smiles
O=C([C@@](CCCC1)([H])N1C(C([C@@]2(O)[C@H](C)C[C@H](OC)[C@@](O2)([H])[C@@H](OC)C[C@@H](C)C/C(C)=C/[C@H]3CC)=O)=O)O[C@H](/C(C)=C/[C@H]4C[C@@H](OC)[C@H](O)CC4)[C@H](C)[C@@H](O)CC3=O
Molecular Formula
C43H69NO12
Molecular Weight
792.01
References & Citations
[1]Hatanaka H, et al. FR-900520 and FR-900523, novel immunosuppressants isolated from a Streptomyces. II. Fermentation, isolation and physico-chemical and biological characteristics. J Antibiot (Tokyo) . 1988 Nov;41 (11) :1592-601.|[2]Krishika Sambyal, et al. Bioprocess and genetic engineering aspects of ascomycin production: a review. J Genet Eng Biotechnol. 2020 Nov 19;18 (1) :73.|[3]Germán Sierra-Paredes, et al. Ascomycin and FK506: pharmacology and therapeutic potential as anticonvulsants and neuroprotectants. CNS Neurosci Ther. Spring 2008;14 (1) :36-46.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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