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Exendin-4, Cy5 labeled (TFA)

CAT: 0804-HY-13443F1Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13443F1Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Exendin-4, Cy5 labeled TFA is a Cy5 labeled Exendin 4. Exendin-4, Cy5 labeled TFA can be used as in vivo β cell tracer. Exendin 4 is a long-acting GLP-1 receptor agonist[1][2].
UNSPSC
12352209
Target
Fluorescent Dye; GCGR
Related Pathways
GPCR/G Protein; Others
Field of Research
Metabolic Disease
Purity
95.16
Smiles
O=C(NCC(N[C@@H](CCC(O)=O)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCSC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CC(N)=O)C(NCC(NCC(N5[C@@H](CCC5)C(N[C@@H](CO)C(N[C@@H](CO)C(NCC(N[C@@H](C)C(N6[C@@H](CCC6)C(N7[C@@H](CCC7)C(N8[C@@H](CCC8)C(N[C@@H](CO)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC9=CNC=N9)NC(CCCCCN(C%10=C(C/%11(C)C)C=C(S(=O)(O)=O)C=C%10)C%11=C\C=C\C=C\C%12=[N+](CC)C(C=CC(S(=O)([O-])=O)=C%13)=C%13C%12(C)C)=O.OC(C(F)(F)F)=O.[x]
Molecular Formula
C217H320N52O67S3.xC2HF3O2
Molecular Weight
4825.37 (free base)
References & Citations
[1]Doyle ME, et al. The importance of the nine-amino acid C-terminal sequence of exendin-4 for binding to the GLP-1 receptor and for biological activity. Regul Pept. 2003 Jul 15;114 (2-3) :153-8|[2]Lehtonen J, et al. Beta cell specific probing with fluorescent exendin-4 is progressively reduced in type 2 diabetic mouse models. Islets. 2015;7 (6) :e1137415.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported

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