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VU0152100 (Standard)

CAT: 0804-HY-13340R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13340R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VU0152100 (Standard) is the analytical standard of VU0152100. This product is intended for research and analytical applications. VU0152100 (VU152100) is a highly selective mAChR positive allosteric modulator (permeable to the blood-brain barrier) . VU0152100 reverses Amphetamine-induced hypermotility in rats and increased levels of extracellular dopamine in nucleus accumbens and caudate-putamen. VU0152100 has good research potential in psychosis and cognitive impairment associated with mental disorders such as schizophrenia[1][2].
CAS Number
409351-28-6
UNSPSC
12352100
Target
MAChR; Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
CC1=C2C(SC(C(NCC3=CC=C(OC)C=C3)=O)=C2N)=NC(C)=C1
Molecular Formula
C18H19N3O2S
Molecular Weight
341.43
References & Citations
[1]Byun NE, et al. Antipsychotic drug-like effects of the selective M4 muscarinic acetylcholine receptor positive allosteric modulator VU0152100. Neuropsychopharmacology. 2014 Jun;39 (7) :1578-93. |[2]Brady AE, et al. Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in rats. J Pharmacol Exp Ther. 2008 Dec;327 (3) :941-53.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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Alternative Products

CatalogName
M26860-01VU0152100
A21769-25VU0152100 25mg
A21769-5VU0152100 5mg
A21769-1VU0152100 1mg
A21769-50VU0152100 50mg
A21769-200VU0152100 200mg
A21769-100VU0152100 100mg
A21769-10VU0152100 10mg
A21769-10mM-DVU0152100 10mM * 1mL in DMSO
abx098968-01Standard

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