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L-650719

CAT: 0804-HY-129781Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-129781Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-650719 is a topical carbonic anhydrase inhibitor (CAI) with a Ki of 10 nM for CA II. L-650719 has shown good intraocular pressure-lowering effects in a rabbit model. L-650719 may be used in glaucoma research[1].
CAS Number
96803-89-3
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Carbonic Anhydrase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Endocrinology
Smiles
O=S(C1=CC2=CC=C(O)C=C2S1)(N)=O
Molecular Formula
C8H7NO3S2
Molecular Weight
229.28
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Bar-Ilan A, Pessah NI, Maren TH. Ocular hypotensive activity and disposition of the topical carbonic anhydrase inhibitor 6-hydroxy-benzo[b]thiophene-2-sulfonamide, L-650,719, in the rabbit. J Ocul Pharmacol. 1989 Summer;5 (2) :99-110.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA II

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