JMV 3008

• Description:

  JMV 3008 is a GHS-R1a antagonist with an IC50 of 5.6 nM. JMV 3008 can be used in the research of diseases such as diabetes and obesity[1].

• UNSPSC:

  12352005

• Target:

  GHSR

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Metabolic Disease

• Smiles:

  O=C ([C@H]1NCCC1) N[C@@H] (C2=NN=C (CCC3=CNC4=C3C=CC=C4) N2CC5=CC=C (OC) C=C5OC) CC6=CNC7=C6C=CC=C7

• Molecular Formula:

  C36H39N7O3

• Molecular Weight:

  617.74

• References & Citations:

  [1]Hanrahan P, et al. Substituted azaquinazolinones as modulators of GHSr-1a for the treatment of type II diabetes and obesity. Bioorg Med Chem Lett. 2012 Mar 15;22 (6) :2271-8.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  GHSR1a

• CAS Number:

  925239-09-4