JMV 3008

• Description :

  JMV 3008 is a GHS-R1a antagonist with an IC50 of 5.6 nM. JMV 3008 can be used in the research of diseases such as diabetes and obesity[1].

• CAS Number :

  [925239-09-4]

• UNSPSC :

  12352005

• Target :

  GHSR

• Related Pathways :

  GPCR/G Protein

• Field of Research :

  Metabolic Disease

• Smiles :

  O=C([C@H]1NCCC1)N[C@@H](C2=NN=C(CCC3=CNC4=C3C=CC=C4)N2CC5=CC=C(OC)C=C5OC)CC6=CNC7=C6C=CC=C7

• Molecular Formula :

  C36H39N7O3

• Molecular Weight :

  617.74

• References & Citations :

  [1]Hanrahan P, et al. Substituted azaquinazolinones as modulators of GHSr-1a for the treatment of type II diabetes and obesity. Bioorg Med Chem Lett. 2012 Mar 15;22 (6) :2271-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  GHSR1a