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Sibofimloc (Standard)

CAT: 0804-HY-12820RSize: 1 EachDry Ice: NoHazardous: No
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Description
Sibofimloc (Standard) is the analytical standard of Sibofimloc. This product is intended for research and analytical applications. Sibofimloc (Antibiotic-202) is a first-in-class, gut-restricted, orally active FimH adhesion inhibitor extracted from patent WO2014100158A1, Compound Example 202. Sibofimloc has anti-bacterial infective activity. Sibofimloc is developed for inflammatory bowel disease (IBD) [1][2].
CAS Number
1616113-45-1
Product Name Alternative
Antibiotic-202 (Standard)
UNSPSC
12352005
Target
Antibiotic; Bacterial; Reference Standards
Related Pathways
Anti-infection; Others
Field of Research
Infection
Smiles
CC(N(CC1)CCC21C3=CC(C#C[C@@H]4[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)=CC=C3C5=CC=C(C#C[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]6O)C=C52)=O
Molecular Formula
C35H39NO11
Molecular Weight
649.68
References & Citations
[1]Ramtohul, Yeeman K, et al. Preparation of mannose derivatives via coupling and click cycloaddition reactions for treating bacterial infections. From PCT Int. Appl. (2014), WO 2014100158 A1 20140626.|[2]W Reinisch, et al. P568 An open-label, multicenter, phase ib, pharmacokinetic (pk) and safety study of a fimh blocker, Sibofimloc (TAK-018/EB8018), in patients with Crohn’s disease (CD), Journal of Crohn's and Colitis, Volume 14, Issue Supplement_1, January 2020: S479–S480.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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Alternative Products

CatalogName
BUP09417-01Sibofimloc
A15512-100Sibofimloc (VRT-1353385, Antibiotic-202) 100mg
A15512-50Sibofimloc (VRT-1353385, Antibiotic-202) 50mg
A15512-25Sibofimloc (VRT-1353385, Antibiotic-202) 25mg
A15512-5Sibofimloc (VRT-1353385, Antibiotic-202) 5mg
A15512-2Sibofimloc (VRT-1353385, Antibiotic-202) 2mg
A15512-10Sibofimloc (VRT-1353385, Antibiotic-202) 10mg
A15512-1Sibofimloc (VRT-1353385, Antibiotic-202) 1mg
A15512-10mM-DSibofimloc (VRT-1353385, Antibiotic-202) 10mM * 1mL in DMSO
abx098968-01Standard

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